Someone on here said you will get as many choices of what to buy, as there are replys. Basically right. However, I notice a lot of people just recommend the calibre they happen to be using, without looking at your case and what would be good for you. The 30-06 has been mentioned most often and in my opinion this is the best calibre for you. I think there is a good chance you will become a handloader and if you do, the 30-06 is ideal, perfect for reloading. Much better than the 308 and head and shoulders better to reload than any of the belted magnums, as well as brass being very abundant and cheap, if you have to buy it. Add to that the fact that many hunters have taken any specie of North American game with the 30-06. In fact, more NA game may have been taken with the 30-06 than any other calibre. There is my 1½ cents worth.